HBM4EU ICI EQUAS report PFAS in serum round 1

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Last Updated: 05-02-2019 12:57

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Within the framework of the HBM4EU project, an Inter-Laboratory Comparison Investigation (ICI) was organized and conducted for the analysis of PFAS (PFAS correspond to 12 biomarkers: PFPeA, PFHxA, PFHpA, PFOA, PFNA, PFDA, PFUnDA, PFDoDA, PFBS, PFHxS, PFHpS, PFOS) in serum. The study was performed from May 2018 to June 2018. Nine different test samples consisting of 5 mL serum each (6 of them spiked with two different concentrations of PFAS (PFASlow, PFAShigh), 3 of them containing native control material (PFASnative) were prepared and sent to the participating laboratories for analysis. Homogeneity and stability assessment of the control materials confirmed that the materials were adequately homogeneous and stable. Laboratory results were rated using z-scores in accordance with ISO 13528 and ISO 17043. The standard deviation for proficiency assessment (also called target standard deviation) was set to FFP = 25 %. In total, 17 laboratories from 11 countries participated in the ICI. The participation in the ICI was satisfactory; 17 out of 17 laboratories submitted their results.