HBM4EU Substances

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The first list of HBM4EU priority substances was identified in 2016 and includes:

  • Aniline family
  • Bisphenols
  • Cadmium and chromium VI
  • Chemical mixtures
  • Emerging substances
  • Flame retardants
  • Polycyclic Aromatic Hydrocarbons (PAHs)
  • Per-/poly-fluorinated compounds
  • Phthalates and Hexamoll® DINCH

A second round of prioritisation was conducted from 2017 to 2018. The second list of HBM4EU priority substances includes:

  • Acrylamide
  • Aprotic solvents
  • Arsenic
  • Diisocyanates
  • Lead
  • Mercury
  • Mycotoxins
  • Pesticides
  • Benzophenones

Information on substance classification, policy-related research questions and research objectives for each substance is captured in the scoping documents for the first and second list of priority substances

These scoping documents formed the basis for the development of activities for inclusion in the annual action plans for HBM4EU. For the most updated version and recent information, please refer to the substance specific webpages.

Work has continuously been developed throughout 2019-2020 for the first and second list of substances. The latest results are available in the Reporting for the first and second set of substances 2020 and on each substance webpage.

A third round of prioritisation is foreseen for 2020 to 2021. The aim of this third round will be to identify priorities for research under a future European human biomonitoring initiative post 2021.


The HBM4EU project was launched in 2016 with the aim of improving the collective understanding of human exposure to hazardous chemicals and developing HBM as an exposure assessment method. The project had €74m in funding and jointly implemented by 120 partners from 28 participating countries – 24 EU member states plus Norway, Switzerland, Iceland and Israel and the European Environment Agency. One of its aims was to ensure the sustainability of HBM in the EU beyond 2021. The project ended in June 2022. The website will not be updated any longer, except the page on peer reviewed publications, but will be online until 2032.