Federica Laguzzi – Karolinska Institute (KI), Sweden
Acrylamide data from Europe – results and policy implications – 28 April – 10:25 am CEST
Several determinants were investigated in relation to urinary biomarkers of acrylamide among 3,157 children (median age:10 years) from Italy, France, Germany and Norway and 1,298 adults (median age:33 years) from Portugal, Spain, France, Germany, Luxemburg and Iceland. More than 96% of the adults and children sampled had urinary acrylamide levels exceeding the European guidance values (16 µg/gcrt). Southern cohorts had higher urinary acrylamide levels than Nordic cohorts. In multi-adjusted analysis, urinary acrylamide levels were higher in relation to high consumption of potato fried and coffee in adults and increasing sampling year (2014-2017) in children. We also observed lower urinary acrylamide levels in relation to high body mass index, intake of fruit/vegetables and cereals in adults and high socioeconomic status, living in rural areas and increasing age in children. Analysis stratified by participating cohorts showed several country differences. In these European cohorts, urinary concentrations of acrylamide were affected by specific dietary and non-dietary determinants in adults and children.
Laguzzi Federica is an Assistant Professor at the Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Sweden. She has a Pharmacy degree (2009), Medical specialization in Food Science (2014) and PhD in Experimental and Clinical Nutrition (2015). Her research activities are focused on cardiovascular disease and cancer epidemiological research in relation to dietary factors with specific focus on dietary fats, circulating fatty acids and gene-fats interactions. She is involved as a coordinator and analyst in epidemiological research based on international collaborative efforts. She has expertise in risk assessment for chemical compounds and holds the role of chemical group leader for acrylamide within HBM4EU.
The HBM4EU project was launched in 2016 with the aim of improving the collective understanding of human exposure to hazardous chemicals and developing HBM as an exposure assessment method. The project had €74m in funding and jointly implemented by 120 partners from 28 participating countries – 24 EU member states plus Norway, Switzerland, Iceland and Israel and the European Environment Agency. One of its aims was to ensure the sustainability of HBM in the EU beyond 2021. The project ended in June 2022. The website will not be updated any longer, except the page on peer reviewed publications, but will be online until 2032.