A13_Data needs for use of HBM in risk assessment

Human biomonitoring (HBM) can be used quite well in a human chemicals risk assessment context. The outcome of this use (comparison of HBM measurements to HBM Guidance Value) can be: Priority or not a priority. If priority, further research e.g. into exposure causes and routes, into differences between subpopulations or hotspots. Higher tier decisions require more relevant data with less uncertainty. So the needs for use of HBM in a risk assessment context depend on the tier as well. The lecture provides needs within the tiered framework. Emphasis is on toxicokinetics and toxicokinetic modelling and the various factors modifying toxicokinetics and so the HBM concentrations measured.